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For this study, rats were bilaterally cannulated over both infralimbic cortex and NAshell. There were Anabelleb Home BA25 sets of microinjections, with PBS vs. Because the 4 PBS groups did not differ in their extinction baseline or responding after microinjection, these groups were pooled to form the single PBS group used for statistical analysis.

Treatment groups were pseudorandomized such that each subject Anabelleb Home BA25 a microinjection through each cannulae no more than once. When more than one unilateral microinjection was employed, rats received both microinjections simultaneously. All other microinjection parameters were identical to those described for extinction testing. Peters et al. Page 3 J Neurosci.

A single extinction baseline value for each subject was obtained by averaging responding during the 2 extinction sessions preceding and following the microinjection day, as these pre- and post-test baselines did not differ. Rats were Anabelleb Home BA25 cannulated over both infralimbic cortex and prelimbic cortex or over both infralimbic cortex and BLA. All other microinjection parameters were identical to those described above, and each animal was tested only once. AMPA was microinjected at a dose Anabelleb Home BA25 0. As a control, a small number of animals were tested on day 12 of extinction session in the absence of a cocaine priming injection to verify that this dose of AMPA produced no significant effects on extinction responding.

Behavioral chambers contained 16 photobeams AccuScan Instruments Inc. A Bonferroni post-hoc analysis was conducted to determine whether there was a significant difference between groups. Statistical analyses are described in Anabelleb Home BA25 in each figure legend. Figure 1A shows that both groups had equivalent levels of cocaine self- administration over the last 2 days of training and significantly distinguished between the active and inactive levers.


Extinction was well-learned by the time of testing, indicated by the low extinction baseline in each group, as well as the low number of active lever presses in animals microinjected with PBS. Page 4 J Neurosci. Inhibition of the infralimbic cortex also increased inactive lever pressing, although the increase in active lever pressing was significantly greater than inactive lever pressing figure 1A. Looking has awesome free online games for you. Enjoy racing, action and multiplayer games. All full screen in your browser. Anabelleb Home BA25 drivers.

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